Ramirez is married to Sean Matzus. Began his experimental/noise work in 1989. Has worked/collaborated with Kapotte Muziek, The Haters/G.X. Jupitter-Larsen, Merzbow, Richard Rupenus (The New Blockaders/NAG), MSBR, Thurston Moore, Con-Dom, Smell & Quim, Macronympha, Das Synthetische Mischgewebe, Astro, Cock ESP, Guilty Connector, Skin Crime, Government Alpha, Prurient, The Rita, Final, John Duncan, Vomir, and others. Ramirez considers The Haters his biggest influence. Ramirez-Matzus has toured/performed in Japan, Europe, Canada, Mexico, and the U.S.
Ramirez was the co-organizer of the festivals: Dead Audio Music Festival and Eyes Behind the Wall. EBTW was the first HNW (harsh noise wall) festival created. Sean E. Ramirez was the co-organizer of these events.